About BioCloud Search EnGene

BioCloud Search EnGene is a web application built on Google’s platform using GAE (Google App Engine).
It adopts a gene-centric approach and enables users to find out information about human genes and gene-drug interactions using a simple ‘Google-like’ query interface that accepts public gene identifiers (e.g. Entrez Gene ID) as keywords.

The application is designed to find and reorganize all the information related to the executed query on Human Genes. The results are re-formatted into a modular view to allow the user to read this information in a more organized and coherent way. BioCloud Search EnGene also takes you straight to the source for further readings. You always end up in the right place.

BioCloud Search EnGene is based on the data contained in the following public data sources:

  • NCBI Entrez
  • Protein Data Bank
  • Uniprot - Universal Protein Resource
  • M.A.T.A.D.O.R. - Manually Annotated Targets and Drugs Online Resource
  • STRING - Known and Predicted Protein-Protein Interactions
  • STITCH - Chemical-Protein Interactions
  • Human Ageing Genomic Resources
  • Cancer Genome Anatomy Project
  • O.M.I.M - Online Mendelian Inheritance in Man
  • REACTOME Pathways
  • Geneontology
  • Ensembl Biomart
  • iHOP - Information Hyperlinked over Proteins
  • Wikigenes Collaborative Publishing
  • HGNC - Hugo Gene Nomenclature Committee
  • HPRD - Human Protein Reference Database
  • Nextprot
  • PIR - Protein Information Resource
  • VEGA - Vertebrate Genome Annotation
  • KEGG - Kyoto Encyclopedia of Genes and Genomes
  • COSMIC - Catalogue of Somatic mutations in Cancer
  • HPA - Human Protein Atlas
  • Gene Cards - The human gene compendium

BioCloud Search EnGene has been designed to find and reorganize information related to Human Genes. It is maintained by Università di Cagliari that authorizes you to access and use BioCloud Search EnGene and the data and information contained on this web application and datastore under the following conditions:

  • BioCloud Search EnGene content can be used and browsed without registering for an account.
  • BioCloud Search EnGene contains information from third party data sources, which may or may not be marked with the name of the source. Such information does not necessarily represent the views or opinions of Università di Cagliari, and Università di Cagliari will have no responsibility whatsoever for such information. All information from third party data sources are the sole responsibility of the person or entity that provides and/or maintains the data source. As a BioCloud Search EnGene user, you are solely responsible for any information that you display, generate, transmit or transfer while using BioCloud Search EnGene, and for the consequences of such actions.
  • BioCloud Search EnGene also contains links to other websites which allow you to leave BioCloud Search EnGene. The application provides these links to you only as a convenience, and the inclusion of any link does not imply endorsement by Università di Cagliari of the third party website or the content or information provided therein. Università di Cagliari does not have any knowledge of or control over the information contained in such other websites. Università di Cagliari will not have any responsibility whatsoever for any information or content contained on those third party websites, links contained on those websites or changes to such websites.
  • Università di Cagliari reserves the right to alter the content of BioCloud Search EnGene in any way, at any time and for any reason, with or without prior notice to you, and Università di Cagliari will not be liable in any way for possible consequences of such changes or for inaccuracies, typographical errors or omissions in the contents hereof.
  • Università di Cagliari also reserves the right to modify these Terms of Use at any time and for any reason, with or without prior notice to you. You should always review the most current Terms of Use herein before using this web application.



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This research was supported by RAS, Regione Autonoma della Sardegna (Legge regionale 7 agosto 2007, n. 7 “Promozione della ricerca scientifica e dell’innovazione tecnologica in Sardegna”) in the project “DENIS: Dataspaces Enhancing the Next Internet in Sardinia”

We thank Glisbo for designing totally non-profit BioCloud Search EnGene logo


Gene type distribution over all annotations


What's BioCloud Search EnGene?

BioCloud Search EnGene (often referred to as BSE) is a web application developed using a platform as a service (PaaS) called Google App Engine.

Why BioCloud Search EnGene is a free service?

BioCloud Search EnGene is a free service because is a university project funded by RAS (Regione Autonoma della Sardegna)

Why BioCloud Search EnGene is built on Google App Engine?

BSE uses Google App Engine because this PaaS (Platform as a Service) has enabled us to build our web application on the same scalable systems that power Google applications. Furthermore this kind of service allows us to maintain the focus on the app development.

Contact us

Our address
Università degli Studi di Cagliari
Dipartimento di Matematica e Informatica
Via Ospedale 72, 09124 Cagliari, Italy


+39 070 675 8757


BioCloud Search EnGene team
Nicoletta Dessì
Gabriele Milia
Emanuele Pascariello
Barbara Pes

Past contributors:
Fabrizio Loddo

What's going on at BioCloud Search EnGene?